CJC-1295 DAC Peptide Guide | Growth Hormone Research

CJC-1295 With Dac Explained: What It Is and How It Works

What is CJC-1295 with DAC?

CJC-1295 with DAC is a synthetic analogue of growth hormone-releasing hormone (GHRH). GHRH is a naturally occurring hormone that plays a key role in regulating the release of growth hormone from the anterior pituitary gland¹.

What does CJC-1295 do?

In peptide research, CJC-1295 is studied for its ability to interact with the GHRH receptor, a receptor involved in endocrine signalling pathways that regulate growth hormone release².

How does CJC-1295 work?

The peptide binds to receptors associated with growth hormone regulation. The addition of the Drug Affinity Complex (DAC) allows the molecule to attach to circulating proteins, increasing its stability in experimental conditions and prolonging receptor interaction³.

Because of these properties, CJC-1295 continues to be investigated in research examining growth hormone signalling and endocrine regulation pathways.

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CJC-1295 With Dac peptide guide

CJC-1295 with DAC is a synthetic peptide analogue of growth hormone-releasing hormone (GHRH). It was developed in research environments to study signalling pathways involved in growth hormone regulation and endocrine system activity.

The peptide is designed to interact with receptors that regulate the release of growth hormone from the pituitary gland. The addition of a Drug Affinity Complex (DAC) allows the molecule to bind to circulating proteins, extending its stability in the bloodstream during experimental studies.

Because of its receptor interaction and modified structure, CJC-1295 with DAC is widely studied in research examining endocrine signalling, growth hormone regulation, and metabolic pathways.

CJC-1295 with DAC: Quick Facts

Key Information	Details
Peptide Name	CJC-1295 with DAC
Peptide Type	GHRH analogue
Full Name	Modified Growth Hormone Releasing Hormone analogue
Molecular Weight	~3647 g/mol
Target Receptor	Growth hormone releasing hormone receptor (GHRH receptor)
Modification	Drug Affinity Complex (DAC)
Research Category	Growth hormone research peptides
Primary Research Areas	Endocrine signalling, growth hormone regulation

Chemical Properties & Molecular Data

CJC-1295 is a modified peptide analogue derived from growth hormone-releasing hormone (GHRH).

The molecule includes structural modifications designed to improve stability and receptor interaction. The addition of the Drug Affinity Complex (DAC) allows the peptide to bind to albumin in circulation, which extends its stability in biological systems.

These modifications make CJC-1295 useful in research investigating how changes to peptide structure influence hormone signalling pathways and receptor activation.

Peptides derived from endocrine hormones are frequently studied in biochemical research exploring hormone signalling and metabolic regulation.

Mechanism of Action

CJC-1295 is primarily investigated for its interaction with GHRH receptor signalling pathways.

Research suggests the peptide may influence:

growth hormone releasing hormone receptor activity
endocrine signalling pathways
pituitary hormone regulation mechanisms
metabolic signalling processes

Activation of the GHRH receptor triggers signalling cascades within the pituitary gland that influence growth hormone release.

These pathways are important for understanding how endocrine signalling regulates metabolic and developmental processes.

Areas of Scientific Research

CJC-1295 has been studied in several areas of endocrine and metabolic research.

Common research topics include:

growth hormone signalling pathways
endocrine system regulation
hormone receptor interaction studies
metabolic signalling research
peptide hormone analogue development

These areas of research aim to better understand how hormone signalling pathways regulate metabolic and physiological processes.

Reconstitution of CJC-1295 with DAC

In research environments, CJC-1295 with DAC is commonly supplied as a lyophilised peptide powder to maintain stability during storage and transport.

Before use in laboratory experiments, the peptide must be reconstituted into solution using a sterile solvent suitable for research purposes. Solvents such as bacteriostatic water or sterile laboratory water are commonly used.

The solvent is typically introduced slowly along the inner wall of the vial to allow the peptide powder to dissolve gradually. Gentle swirling may assist dissolution, while vigorous shaking is generally avoided to maintain peptide stability.

Researchers often determine the desired solution concentration before preparing peptide solutions. You can use our Peptide Calculator to estimate dilution ratios and final concentrations based on vial strength and solvent volume.

Storage of CJC-1295 with DAC

Proper storage conditions are important for maintaining the stability and integrity of research peptides.

Lyophilised peptides are generally stored in cool, dry laboratory conditions, often under refrigeration or freezing temperatures to preserve long-term stability.

Protecting peptide samples from moisture, light exposure, and repeated temperature fluctuations helps minimise degradation.

After reconstitution, peptide solutions are typically stored at lower temperatures and handled according to standard laboratory practices to maintain stability during research experiments.